COMPUTATIONAL ANALYSIS OF RNA METHYLTRANSFERASE RV3366 AS A POTENTIAL DRUG TARGET FOR COMBATING DRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS

Computational analysis of RNA methyltransferase Rv3366 as a potential drug target for combating drug-resistant Mycobacterium tuberculosis

Mycobacterium tuberculosis (M.tb) remains a formidable global health threat.The increasing drug resistance among M.tb clinical isolates is exacerbating the current tuberculosis (TB) High Temperature Grease burden.In this study we focused on identifying novel repurposed drugs that could be further investigated as potential anti-TB drugs.We utilized

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Distribution of coccoliths in surface sediments across the Drake Passage and calcification of Emiliania huxleyi morphotypes

The Southern Ocean is experiencing rapid and profound changes in its physical and biogeochemical properties that may influence the distribution and composition of pelagic plankton communities.Coccolithophores are the most prolific carbonate-producing phytoplankton group, playing an important role in Southern Ocean biogeochemical cycles.However, kno

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